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Spontaneous Spinal Epidural Hematoma Caused by Anticoagulant Therapy: Report of a Case

因使用抗凝血劑引發之急性脊椎硬腦膜外出血:病例報告

摘要


脊椎的急性硬腦膜外出血在臨床上是極為少見的病例,通常此類的病患往往合併有凝血功能的異常或是血管本身的病變,如動靜脈畸形等等。我們提出一位29歲的男性病患,在使用抗凝血劑之後數小時引起急性下背痛,且合併有失禁及下肢無力的症狀。在核磁共振檢驗之下,發現有脊椎自發性的急性硬腦膜外出血,因此,緊急採取手術減壓及血塊清除,術後病患症狀得到了顯著的改善。我們將回溯文獻有關於脊椎急性硬腦膜外出血的臨床症狀、手術治療及預後,並討論緊急手術和其預後的關聯。

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並列摘要


The rapid expansion of indications for anticoagulant therapy in recent years suggests a need to consider the spinal epidural hematoma. We present a 29 year-old male with a history of coumadin therapy for deep vein thrombosis who developed exsanguinating lower back pain and progressive neurological deterioration. Under the emergent magnetic resonance imaging (MRI), a thoracolumbar junction spinal epidural hematoma was found. Laminectomy and evacuation of hematoma were performed. Several cases reported in the past literature are reviewed and the possible pathogenesis and treatment are also discussed.

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