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Multiple Subpial Transection: Report of a Case

多處軟膜下腦迴橫切術:病例報告

摘要


對於無法以藥物良好控制的頑固性癲癇,以外科手術方式切除異常放電的大腦皮質,可以獲得不錯的癲癇控制。然而,對位於大腦功能皮質的癲癇病灶而言,手術切除往往導致嚴重的神經功能損傷。近年來,一種新的手術方式一多處軟膜下腦迴橫切術,對位於大腦功能皮質的異常放電區域,提供了不錯的癲癇控制,同時,不至於引起不可逆的神經功能損傷。在此,我們回顧了相關文獻,並且對這種新的手術方式加以討論。

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並列摘要


Multiple subpial transection (MST) is a surgical technique designed for use in patients whose epileptic foci are located in high functional cortical areas such as the primary sensorimotor cortex and the language cortex. Theoretically, MST disrupts horizontal neuronal interconnections that are essential to the spreading of seizure, while preserving the intrinsic columnar organization of the brain. MST thus interrupts the synchronization of epileptic neurons while sparing input, output and vascular supply. This report describes the case of a 23-year-old woman with seizure disorder that lasted for 17 years. The epileptic foci located in the motor cortex were noted following chronic subdural plate electrocorticographic (ECoG) recording. MST was performed and the patient exhibited a Class 11 surgical outcome. This new surgical technique for treating medical intractable epilepsy will be discussed.

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