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Non-small Cell Lung Cancer with Superior Vena Cava Syndrome Effectively Treated with Implantation of Intravascular Stent and Chemotherapy-A Case Report and Review of the Literature

血管內支架併化學治療在非小細胞肺癌合併上腔靜脈症候群時的使用-病例報告及文獻回顧

摘要


上腔靜脈症候群是由於上腔靜脈阻塞或狹窄所引起,其肇因有惡性腫瘤或良性病灶。常見的惡性腫瘤主要是肺癌和縱隔腔腫瘤。治療模式必須根據其潛在病因。在傳統治療上,有外科燒道手術、體外放射線治療、化學治療及內科療法。根據過去的病例報告,本科為1位肺癌病患植入血管內支架及合併化療藥劑,成功有效減小腫瘤體積及解除症狀。然而,在後續追蹤卻發現支架移位現象,或由於腫瘤體積縮小以致血管擴大所致。因此,慎選支架大小並考慮腫瘤縮小可能的影響是非常重要的。

並列摘要


Superior vena cava syndrome is caused by obstruction of the superior vena cava due to a variety of malignant and benign entities. The most common malignant entities are lung cancer and mediastinal tumor. Conventional treatments include bypass surgery, external beam radiation therapy, chemotherapy, and medical treatment. In this report, we performed an intravascular metallic stent deployment and combined chemotherapy with Vinorelbine in a case of non-small cell lung cancer with superior vena cava syndrome. The tumor regressed and symptomatic improvement was achieved after 124 days of follow-up. However, stent migration was noted and possibly due to tumor shrinkage and subsequent luminal enlargement. The choice of stent size is critical and should allow for possibility of tumor regression.

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