A premature neonate with gestational age of 32 weeks and birth body weight of 1650 grams was diagnosed to have type A interrupted aortic arch, perimembranous type ventricular septal defect, atrial septal defect, and patent ductus arteriosus. One-stage complete reconstruction of aortic arch and concomitant repair of intracardiac defects was performed at age of 13 days with body weight of 1600 grams. Through innominant artery and retrocardiac descending aorta cannulation for continuous cerebral and lower body perfusion, deep hypothermic circulatory arrest was avoided. Postoperative renal function was excellent, and there were no neurological sequelae after 24 months' follow-up.