- 期刊
In-Hospital and Long-Term Results of Unprotected Main Stenting Versus Coronary Artery Bypass Grafting-A Single Center Experience in Taiwan
並列摘要
Background: The status of percutancous coronary intervention (PCI) for the treatment of left main coronary artery (LMCA) disease remains undetermined, and relatively few data On Taiwanese population has been published. Method: Between March. 2003 and October, 2008. 121 patients with de-novo significant LMCA disease were included into this study. Eighty-seven patients received coronary artery bypass surgery (CABG) for LMCA disease, and 34 patients received PCI for LMCA disease. Significant LMCA disease was defined as at least＞50% stenosis of the left main coronary artery. The differences of clinical outcomes between the two treatment strategies were compared with respect to the in-hospital major adverse events rate and long-term major adverse cardiovascular and cerebrovascular events (MACCE) rate. Results: There were no significant differences in terms of baseline characteristics between the two groups. The overall all-cause mortality with MACCE was 32.2% in the CABG group, and 35.3% in the PCI group (p=0.74). The overall mortality throughout the study period was 17.2% in the CABG group, and 5.9% in the PCI group (p=0.09). The CABG group had significantly higher in-hospital major adverse event rates (27.6%) than the PCI group (8.8%) (p=0.02) after adjustment of potential covariates. Long-term cumulative MACCE rates were 15% in the CABG group, and 32.4% in the PCI group. respectively (p=0.02). The lower MACCE rate in the CABG group was mainly due to lower revascularization rate in the CABG group than in the PCI group (8.8% vs. 29.4%; p ＜0.01). Conclusion: The CABG group conferred significantly higher in-hospital major adverse event rate hut significantly lower long-term MACCE rate in patients with significant LMCA disease. The CABG group displayed numerically higher incidence of all-cause mortality throughout the study period. PCI could he considered an alternative option for patients with unprotected LMCA disease.
延伸閱讀
- Tsai, W. C., Wu, K. Y., Lin, G. M., Chen, S. J., Lin, W. S., Yang, S. P., Cheng, S. M., & Lin, C. S. (2017). Clinical Characteristics of Patients Less than Forty Years Old with Coronary Artery Disease in Taiwan: A Cross-Sectional Study. Acta Cardiologica Sinica, 33(3), 233-240. https://doi.org/10.6515/ACS20161026A
- Chung, J. H., Li, M. H., Chen, C. H., Hsu, M. J., Yang, C. H., & Tuan, S. H. (2021). Association between Physical Function and Quality of Life among Older Adults after Coronary Artery Bypass Graft Surgery in Taiwan. 醫學與健康期刊, 10(2), 43-60. https://www.airitilibrary.com/Article/Detail?DocID=23046856-202107-202108160009-202108160009-43-60
- Hii, C. H., Chien, H. H., & Juan, C. W. (2013). The Clinical Characteristics and Outcomes of In-Hospital Cardiac Arrest Patients with Successful Resuscitation in a Teaching Hospital in Central Taiwan. 中華民國急救加護醫學會雜誌, 24(3), 77-88. https://www.airitilibrary.com/Article/Detail?DocID=10232214-201309-201409100002-201409100002-77-88
- 門朝陽、閻紫宸、萬建成、鄭初發、郭傑、莊士易、李明憲（1999）。A Comparison of Non-Uniformed Attenuation Correction Aided 201Tl Myocardial Perfusion SPECT and Cardiac Catheterization in Coronary Artery Disease of Taiwanese。核子醫學雜誌，12(4)，175-180。https://www.airitilibrary.com/Article/Detail?DocID=1022923x-199912-12-4-175-180-a
- 程毅君、蔡政憲、鄭宇庭（2008）。Risk Assessment of Coronary Artery Bypass Grafting Surgery: An Empirical Study of Taiwan。風險管理學報，10(2)，183-218。https://doi.org/10.30003/JRM.200807.0003