- 期刊
Evaluation of Echocardiographic Epicardial Fat Thickness as a Sign of Cardiovascular Risk in Positive Exercise Test Patients
並列摘要
Background: The association between epicardial fat thickness (EFT) and positive exercise test results for the diagnosis of coronary artery diseases (CAD) has yet to be evaluated. This study assessed the predictive value of EFT for CAD on the angiographs of patients with positive exercise tests. Methods: A total of 91 subjects were chosen consecutively fromstable angina pectoris patients who were referred for coronary angiography due to a positive exercise test result. The EFT measures were obtained by echocardiographic parasternal long-axis views on the free wall of the right ventricle at end-systole of three cardiac cycles. Gensini scores were calculated by a conventional coronary angiography technique using a calculation method previously defined. Results: Receiver operator characteristic (ROC) curve analysis revealed a 0.65 cm (95% confidence interval: 0.628, 0.832, p ＜ 0.001) area under the curvewith 74.3% sensitivity and 62.3% specificity at the cut-off value of EFT for the prediction of critical coronary artery stenosis. Following ROC curve analysis, two groups were defined according to EFT cut-off value (groups 1 and 2). The severe coronary stenosis ratio was significantly higher in group 2 compared to group 1 (31.9 % vs. 11%, p ＜ 0.001) and Gensini scores were significantly higher in group 2 (6.3 ± 13.3 vs. 16.5 ± 17.9; p ＜ 0.001). There was no significant correlation between Gensini scores and EFT in group 1 (r = 0.093, p = 0.549), but therewas a strong significant correlation in group 2 (r = 0.730, p ＜ 0.001). Linearmultivariate regression analysis revealed that EFT (＞ 0.65 cm) was the only independent risk factor for critical coronary artery stenosis (β= 0.451, p ＜ 0.001). Conclusions: EFT was significantly correlated with the severity and prevalence of coronary artery disease in positive exercise test patients.
延伸閱讀
- Mandeville, J. C., & Colebourn, C. L. (2012). Can Transthoracic Echocardiography Be Used to Predict Fluid Responsiveness in the Critically Ill Patient? A Systematic Review. Critical Care Research and Practice, 2012(), 331-339. https://doi.org/10.1155/2012/513480
- Catanzaro, J. N., Makaryus, J. N., Makaryus, A. N., Sison, C., Vavasis, C., Fan, D., & Jadonath, R. (2014). Echocardiographic Predictors of Ventricular Tachycardia. Clinical Medicine Insights: Cardiology, 2014(S4), 37-42. https://doi.org/10.4137/CMC.S18499
- Rameh, V., & Kossaify, A. (2016). Appropriate Use Criteria in Echocardiography: An Observational Institutional Study with the Perspective of a Quality Improvement Project. Clinical Medicine Insights: Cardiology, 2016(), 23-28. https://doi.org/10.4137/CMC.S36504
- 張宏謀（1987）。Echocardiographic Study for Predicting the Prognosis in Patients with Chronic Congestive Heart Failure。The Kaohsiung Journal of Medical Sciences，3(11)，689-694。https://doi.org/10.6452/KJMS.198711.0689
- Lin, J. L. (2015). From Fat to Heart: The Associations among Epicardial Adiposity, Cardiometabolic Profiles and Heart Failure with Preserved Ejection Fraction [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2015.02771