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Dense Deposit Disease Associated with Cryoglobulinemia:A Case Report
第二型膜性增生性腎絲球腎炎及冷凝球蛋白血症—病例報告
摘要
第二型膜性增生性腎絲球腎炎（membranoproliferative glomerulonephritis type II）又稱為dense deposit disease，在中國人極少被報告。在此我們報告一個患此病的臺灣女孩，她表現出下肢水腫、蛋白尿、及正常血清肌酐酸值已經八年。住院時她有腎病症候群和冷凝球蛋白症（cryoglobulinemia）。腎臟切片組織在光學顯徵鏡下呈現如膜性腎絲球腎炎（membranous glomerulonephritis）的表現，在電子顯徵鏡下可見到的特徵為基底膜內的深色帶狀沉積。就我們所知這是在文獻上第一個同時有dense deposit disease及冷凝球蛋白血症的病例報告。
關鍵字
無資料並列摘要
Dense deposit disease, also known as membranoproliferative glomerulonephritis (MPGN) type II, is rarely reported in Chinese. Herein we reported a case of this disease in a Chinese girl in Taiwan. She had edema and proteinuria, but normal serum creatinine, for 8 years. When the renal biopsy performed, she had manifestations of nephritic syndrome and cryoglobulinemia. The histological feaures resembled membranous nephropathy on hematoxyline-eosin stain. Electron microscopy revealed characteristic intramembranou dense deposits. To our knowledge, this is the first case of dense deposit disease associated with cryglobulinemia reported.
並列關鍵字
無資料延伸閱讀
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