Renal Biopsy in Aged Patients-12 Years Experience in Taiwan Cathay General Hospital

Yi-Ann Chen ； Chwei-Shiun Yang

《Acta Nephrologica》 21卷2期 (2007/06) Pp. 97-103

並列摘要

Background: Renal disease in the elderly is common and often considered to be the result of aging or hypertensive changes. Nevertheless, the incidence and causes of renal disease in elderly patients (≥70) in Taiwan remains unclear.
Methods: We did a single-center, retrospective study (1994-2005) of elderly patients with renal disease that was documented by renal biopsy. The pathologic findings were also compared elderly patients of age under 70.
Results: Among 877 renal biopsies, 95 were for patients aged 70 or older; mean age was 73.3 (70-89 years old); male: female was 59:36. Nephrotic syndrome (46.3%) and acute renal failure (35.8%) were the most common reasons for renal biopsy; chronic renal failure (10.5%) and asymptomatic urinary abnormalities (7.4%) were less common. Among 44 cases of nephrotic syndrome, the most common causes were: membranous nephropathy (n=19) ＞ diabetic nephropathy (9) ＞ focal or global segmental glomerulosclerosis (6) ＞membranoproliferative glomerulonephritis (4). In acute renal failure group, crescentic glomerulonephritis was most common (7/34). Tubulointerstitial diseases were seen more frequently in the elderly. In chronic renal failure group, chronic interstitial nephritis was the most common cause. Asymptomatic urinary abnormalities were the least indication for elderly people than in younger patients (7.4% vs 23%).
Conclusion: We conclude that renal biopsy indication and pathological findings in the elderly are different from other age groups. Renal biopsy provides useful information for pertinent treatments, especially for acute renal failure or nephrotic syndrome in patients over 70.

並列關鍵字

Aged ； renal biopsy ； renal disease