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- OpenAccess
Risk Factors for Residual Renal Function Decline in Incident Peritoneal Dialysis without Diabetes
摘要
BACKGROUND: Residual renal function (RRF) protection is important for good prognosis in patients undergoing peritoneal dialysis (PD). This study investigated potential risk factors for RRF decline in nondiabetic incident PD patients. METHODS: This study retrospectively analyzed patient medical records from 42 subjects from October 2012 to October 2013 in one hospital-facilitated PD center. Patients with diabetes or history of diuretics use were excluded. The study parameters included demographics, blood examination results, PD-related factors, medications, and comorbidities. Fast RRF decline was defined as a decline rate of ＞ 50% in a single year, while slow RRF decline was defined as a decline of ＜ 50% or no decline over the same time. Logistic regression was used for data analysis. RESULTS: Slow and fast RRF decline was seen in 30 and 12 patients, respectively. No significant differences were seen in the baseline blood parameters, PD-related factors, medications, or comorbidities. Higher creatinine and uric acid levels were observed in patients with fast RRF decline. Univariate analysis, but not multivariate analysis, revealed that serum creatinine and uric acid levels were significant risk factors for RRF decline. CONCLUSION: Our results find that baseline creatinine and uric acid levels may be independent risk factors for RRF decline in non-diabetic incident PD patients.
延伸閱讀
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