- 期刊
- OpenAccess
Proteinuria Enhances Prediction Ability of Sequential Organ Failure Assessment Score and Associated with Mortality in Coronary Care Units
摘要
BACKGROUND: Proteinuria is associated with increased morbidity and mortality in patient with cardiac surgery. This investigation explored the impact of proteinuria and its association with the outcomes of patients in coronary care units (CCUs). METHODS: This retrospective study analyzed the CCU medical records between December 2010 and June 2012 of a tertiary care university hospital. Three-month mortality and hospital stay were identified as outcomes. Acute Physiology and Chronic Health Evaluation (APACHE) III and sequential organ failure assessment (SOFA) scores were calculated at admission. RESULTS: A total of 305 adult patients with a mean age of 64.9 years were investigated. Intensive care unit (ICU) stay and hospital stay were longer and the risk of 3-month mortality was higher in patients with proteinuria. Multivariate logistic regression analysis revealed that proteinuria was an independent factor, after adjusting for clinical factors. The incremental prognostic value of proteinuria and SOFA scores was significantly higher than that of SOFA alone (area under the receiver operating characteristic curve [ΔAUROC] = 0.063, P = 0.030). CONCLUSION: CCU patients with proteinuria had poor short-term outcomes and longer hospital stays. Proteinuria enhanced the ability of outcome prediction of SOFA. Urinary proteinuria is a cheap and easytouse tool for identifying high-risk patients.
延伸閱讀
- Lin, C. H., Yeh, J. K., Lin, T. Y., Lo, Y. L., Chang, P. J., Ju, J. S., Chiu, T. H., Tung, P. H., & Lin, S. M. (2021). Risk Factors for 5-year Mortality in Patients Hospitalized with Congestive Heart Failure and Chronic Obstructive Pulmonary Disease. 胸腔醫學, 36(1), 18-27. https://www.airitilibrary.com/Article/Detail?DocID=10239855-202103-202104150013-202104150013-18-27
- Ting, J. T., Wu, H. C., Wang, W. J., Chen, Y. W., Chen, H. H., & Lo, Y. W. (2014). The Duration of Postoperative Acute Kidney Injury Predicts In-Hospital Mortality in Critically III Patients after Non-Cardiac Surgery. Acta Nephrologica, 28(2), 83-92. https://doi.org/10.6221/AN.2014003
- 鄭綺（1999）。An Investigation of Maximal Oxygen Uptake, Fitness Self-Efficacy, and Quality of Life Among Coronary Artery Bypass Graft Patients。護理研究，7(6)，531-542。https://doi.org/10.7081/NR.199912.0531
- Yeh, T. C., Chang, H. H., Wang, J. O., Kao, S., Lin, T. C., & Ho, S. T. (2022). Age and Comorbidities as Predictors of Hospital Mortality in Adult Patients Who Receive Extracorporeal Membrane Oxygenation Therapy: A Population-based Study. Journal of Medical Sciences, 42(3), 120-126. https://doi.org/10.4103/jmedsci.jmedsci_128_21
- Wang, W. T., Hsi, C. N., Lin, H. J., Chou, C. Y., Wang, S. H., Chen, H. C., & Chang, C. T. (2018). The Optimal Cut-off Value of Abdominal Aortic Calcification Score in Predicting Mortality in Chronic Hemodialysis Patients. Acta Nephrologica, 32(4), 160-166. https://doi.org/10.6221/AN.201812_32(4).0003