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Blood Infection by Mycobacterium Chelonae in a Uremic Diabetes Patient

糖尿病尿毒症病患由龜分枝桿菌引起之血行感染

摘要


龜分枝桿菌(Mycobacterium chelonae)的血行感染比較罕見,本案例爲一位五十歲女性病患有糖尿病併發尿毒症,在接受人工動靜脈廔管植入術兩個月後出現畏寒、顫抖及高燒症狀,多次血液培養呈現陽性反應,經由次培養後,菌落塗片Kinyoun染色顯示有抗酸性桿菌,使用聚合酶鏈鎖反應合併核酸限制酶截切多型性分析法鑑定結果為龜分枝桿菌感染。龜分枝桿菌為快速生長菌且對許多抗生素具有抗藥性,醫院臨床微生物實驗室應建立並提供快速診斷方法以因應這種非結核分枝桿菌的感染。

並列摘要


This regards a rare case of blood infection with a nontuberculous mycobacterium, Mycobacterium chelonae. A 50-year-old woman with uremic diabetes presented symptoms of aversion to cold, trembling and high fever at two months after an implant surgery of arteriovenous fistula. Multiple blood cultures all indicated positive results of bacterial infections. After subculture, a Kinyoun-stained smear revealed that the infected bacteria are acid-fast mycobacteria. Results of polymerase chain reaction coupled restriction fragment length polymorphism analysis concluded the M. chelonae infection. Since M. chelonae is fast growing and usually has multiple drug resistance, laboratories in hospitals should establish and provide rapid diagnostic methods for such nontuberculous mycobacterium infections.

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