志賀毒性大腸桿菌（STEC）的臨床實驗室檢驗

Diagnosis of Shiga Toxin- Producing Escherichia coli (STEC)Infections by Clinical Laboratory

陳星宇(Hsing-Yu Chen) ； 孫俊仁(Jun-Ren Sun)

《Journal of Biomedical & Laboratory Sciences》 23卷4期 (2011/12) Pp. 127-133

https://doi.org/10.30046/JBLS.201112.0001

摘要

人類如果感染志賀毒性大腸桿菌（shiga toxin－producing Escherichia coli，STEC）會造成嚴重腹瀉。即時且適當的診治可以減少病人併發嚴重腎臟疾病及改善病人預後。所以實驗室如何正確診斷志賀毒性大腸桿菌就很重要。以群聚感染爆發與感染控制的角度而言，實驗室必須能區分所流行的志賀毒性大腸桿菌血清型。本篇文章為介紹臨床實驗室診斷志賀毒性大腸桿菌的檢驗流程。此流程包含腹瀉檢體的採集及運送、針對志賀毒性大腸桿菌的培養及非培養的相關鑑定試驗。在台灣，志賀毒性大腸桿菌所造成的群聚感染並不常見，主要是跟我們熟食的飲食習慣有關。但隨著生食主義及生機飲食的盛行，志賀毒性大腸桿菌感染的風險也相對提高。臨床實驗室了解如何快速檢測志賀毒性大腸桿菌感染就顯得格外重要。

關鍵字

志賀毒性大腸桿菌 ； 志賀毒素

並列摘要

Infection with shiga toxin -producing Escherichia coli (STEC) causes diarrhea in humans. Accurate diagnosis of STEC infection by clinical laboratory is important because appropriate treatment early might decrease the risk for serious complications such as renal damage and improve patient outcome. The differentiation of STEC serotypes is essential for outbreak responses and infection control. This article describes the procedure of STEC diagnosis in clinical laboratory. The procedure including the diarrhea specimen handling and transport; a review of culture and non-culture experiments for STEC diagnosis. In Taiwan, STEC infection is uncommon because of the eating habit of cooked food. But the risk of STEC infection is higher than before because the prevalent fashions of feed raw foodism and living food die. It is important to know how to rapidly diagnose STEC infection in clinical laboratory.

並列關鍵字

shiga toxin-producing Escherichia coli ； shiga toxin