The Gut Microbiota in Human Health and Disease: From Brain-Gut Axis Testing Methodologies to Therapeutic Approaches

Microbes are the most abundant form of life on earth; yet their diversity is under-appreciated. Owing to a better understanding of their involvement in host pathophysiology, investigation of the human microbiota has been put under the spotlight. This mini-review briefly summarizes gut microbiota analysis methods, the brain-gut axis, as well as the application of microbiota-based therapy using prebiotics or probiotics.

關鍵字

Gut microbiota ； molecular fingerprinting ； brain-gut axis ； prebiotic ； probiotic

並列摘要

微生物是地球上最豐富的生命形式，然而其多樣性卻未能被充分認識。目前對微生物群參與宿主的生理與病理機制有更多的瞭解，因此人類微生物群的研究已成為了眾所注目的焦點。此短篇綜論主要為總結人類腸道微生物群的檢驗方法與腦腸軸的機制，以及益生元或益生菌為治療基礎的應用。

並列關鍵字

腸道菌群；分子指紋圖譜；腦腸軸；益生元；益生菌

延伸閱讀

Lin, T. L., Lu, C. C., Lai, W. F., Wu, T. S., Lu, J. J., Chen, Y. M., Tzeng, C. M., Liu, H. T., Wei, H., & Lai, H. C. (2020). 以腸道微生物相為基礎的整合多體學研究：次世代中醫草藥學研究. Journal of Biomedical & Laboratory Sciences, 32(2), 60-75. https://www.airitilibrary.com/Article/Detail?DocID=10137653-202006-202006200006-202006200006-60-75
Fang, K. C. (2020). 腸道微菌叢移植在菌叢失衡腸道疾病的效果:統合分析與系統性回顧 [master's thesis, Taipei Medical University]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0007-3007202009351100
吳造中、陳明汝（2021）。以腸道微生物群為標的作為心血管疾病的治療方法。台灣醫學，25(5)，559-568。https://doi.org/10.6320/FJM.202109_25(5).0001
陳信豪、林啟民、葉姿麟（2020）。腸道微菌叢與腸腦軸線於人體疾病角色之探討。家庭醫學與基層醫療，35(4)，88-94。https://www.airitilibrary.com/Article/Detail?DocID=P20090727001-202004-202004290016-202004290016-88-94
譚健民、鄭美美、潘建志（2020）。腸道菌群在神經精神科疾病的致病機制：兼論益生菌在腸腦軸的角色。臺灣醫界，63(8)，16-22。https://www.airitilibrary.com/Article/Detail?DocID=17263603-202008-202008070016-202008070016-16-22

國際替代計量

The Gut Microbiota in Human Health and Disease: From Brain-Gut Axis Testing Methodologies to Therapeutic Approaches

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