- 期刊
Comparison of Respiratory Function between Parkinsonian Patients and Normal Subjects
巴金森氏病患與正常人呼吸功能的比較
摘要
The major purposes of this study were to compare the respiratory function between Parkinsonian patients and normal subjects, and also to examine the possible factors affecting the respiratory muscle strength. Eleven patients in Hoehn and Yahr stage Ⅰ and Ⅱ (with mild disability) were classified as group P1. Ten patients in Hoehn and Yahr stage Ⅲ and Ⅳ (with moderate disability) were classified as group P2. Eight age-, height-, and weight-matched normal subjects were chosen as control group C. The respiratory function was assessed in a sitting position. The results indicated that:(1) the maximal inspiratory pressure (PImax) of inspiratory muscles and the maximal expiratory pressure (PEmax) of expiratory muscles in group P2 were 50.8 cmH2O and 50.6cmH2O, respectively, which were significantly (p＜0.05) lower than that in group PI (94.4 cmH2O and 89.6 cmH2O, respectively) and group C (115.3 cmH2O and 100.9 cmH2O, respectively); (2) the forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) in group P2 were 1.8L and 1.3L, respectively, which were significantly (p＜0.05) lower than that in group P1 and group C; (3) PImax and PEmax correlated significantly (p＜0.05) with the FVC and FEV1, respectively; (4) the severity of disease and the level of exercise were highly related to P1max (p＜0.01). These findings suggest that the respiratory function is not significantly reduced in Parkinsonian patients with mild disability. The severity of disease and the level of exercise may contribute to the decrease of respiratory muscle strength in Parkinsonian patients.
並列摘要
The major purposes of this study were to compare the respiratory function between Parkinsonian patients and normal subjects, and also to examine the possible factors affecting the respiratory muscle strength. Eleven patients in Hoehn and Yahr stage Ⅰ and Ⅱ (with mild disability) were classified as group P1. Ten patients in Hoehn and Yahr stage Ⅲ and Ⅳ (with moderate disability) were classified as group P2. Eight age-, height-, and weight-matched normal subjects were chosen as control group C. The respiratory function was assessed in a sitting position. The results indicated that:(1) the maximal inspiratory pressure (PImax) of inspiratory muscles and the maximal expiratory pressure (PEmax) of expiratory muscles in group P2 were 50.8 cmH2O and 50.6cmH2O, respectively, which were significantly (p＜0.05) lower than that in group PI (94.4 cmH2O and 89.6 cmH2O, respectively) and group C (115.3 cmH2O and 100.9 cmH2O, respectively); (2) the forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) in group P2 were 1.8L and 1.3L, respectively, which were significantly (p＜0.05) lower than that in group P1 and group C; (3) PImax and PEmax correlated significantly (p＜0.05) with the FVC and FEV1, respectively; (4) the severity of disease and the level of exercise were highly related to P1max (p＜0.01). These findings suggest that the respiratory function is not significantly reduced in Parkinsonian patients with mild disability. The severity of disease and the level of exercise may contribute to the decrease of respiratory muscle strength in Parkinsonian patients.
延伸閱讀
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