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Eosinophilic Gastroenteritis in a Patient with Helicobacter Pylori Gastritis

嗜伊紅性胃腸炎合併幽門螺旋桿菌胃炎

摘要


嗜伊紅性胃腸炎是一種慢性浸潤性且較少見的胃腸炎,胃腸道的症狀以腹痛、噁心及腹瀉最常見。臨床症狀嗜伊紅性白血球主要侵犯的胃腸壁層為主。幽門螺旋桿菌已被証實與許多胃腸疾病有關,包括慢性胃炎、胃及十二指腸潰瘍、胃黏膜相關淋巴瘤以及胃癌。本文報告一56歲女性主訴噁心、嘔吐、腹瀉、腹部疼痛及體重減輕。末稍血液嗜伊紅性白血球增加及有明顯胃腸炎症狀。上腸胃道內視鏡胃的黏膜切片發現有幽門螺旋桿菌感染及嗜伊紅性白血球侵犯胃黏膜層。確定診斷為嗜伊紅性胃腸炎合併幽門螺旋桿菌胃炎,經根除幽門螺旋桿菌及類固醇治療後,病人在門診追蹤治療迄今並無復發跡象。

並列摘要


Eosinophilic gastroenteritis is an uncommon chronic disease of the gastrointestinal tract that is characterized by abdominal pain, nausea, and diarrhea. Eosinophilic infiltration of the gut wall is pathognomonic of the disease. Helicobacter Pylon (H. pylori) is associated with a wide spectrum of gastroduodenal diseases. Strong evidence has shown that H. pylori is implicated in the development of gastritis, gastric and duodenal ulcers, MALT lymphoma and gastric cancer The case reported is a 56-year-old female presenting with nausea, vomiting, diarrhea, epigastric discomfort and weight loss. The clinical picture was characterized by peripheral eosinophilia. Upper gastrointestinal (UGI) panendoscopy revealed H. pylori infection and eosinophilic infiltration of the mucosal layer of the stomach wall. A diagnosis of eosinophilic gastroenteritis as well as H. pylori gastritis was made. The patient experienced an impressive response to eradication of H pylon and steroid therapy.