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Spontaneous Candida Peritonitis in Patients with Liver Cirrhosis: Report of Two Cases

自發性白色念珠菌腹膜炎:兩病例報告

摘要


自發性細菌腹膜炎常發生於嚴重肝硬化的病人,致病菌通常來自正常腸胃道內的細菌。以往文獻報告中,很少提及由白色念珠菌感染而致的自發性腹膜炎。在這篇報告,我們報告二位肝硬化的病人在診斷自發性腹膜炎後,以一般抗生素治療仍無反應,腹水經反覆培養後,發現均有白色念珠菌的感染。在使用抗徽菌藥物治療後,腹水再次檢查及培養顯示病人對抗徽菌藥物有反應。於文獻回顧後,我們發現只有五例白色念珠菌造成自發性腹膜炎的病例報告。因此,雖然白色念珠菌造成自發性腹膜細菌造成自發性腹膜炎少見,臨床醫師在治療肝硬化病人的腹膜炎時,仍要將魄念珠菌感染考慮是可能的致病菌之一。

並列摘要


Spontaneous bacterial peritonitis is a common and severe infection occurring in patients with decompensated liver cirrhosis. Most of the causative pathogens are normal enteric flora. Spontaneous fungal peritonitis rarely occurs in such patients. We report two cases with decompensated liver cirrhosis and spontaneous peritonitis due to Candida albicans. Both patients had advanced liver cirrhosis, and peritonitis developed after episodes of massive gastrointestinal bleeding. Aliterature review showed that five previously reported cases involved spontaneous Candida peritonitis. Although rare, fungal infections should be considered in patients with spontaneous peritonitis and liver cirrhosis.

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