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Multimodality Treatment for Anal Cancer-A Case Report and Literature Review

多科整合治療肛門癌-病例報告及文獻回顧

摘要


化學放射同步治療用於侷限性肛門癌始於一九七○年代,我們報告一位四十二歲病人罹患局部侵犯性肛門扁平上皮細胞癌。我們給予原發腫瘤及骨盆腔合併雙側腹股溝放射治療共5040cGy。化學治療則為5-fluorouracil 1000mg/平方公尺,於放射治療之第一至四日及第二十九至三十二日連續輸注,另加mitomycin-C 10mg/平方公尺,於第一日靜脈注射。病人於治療結束後第六週之追蹤時已發現達到完全緩解,並且在接下來三十六個月的追蹤仍然維持在無病存活的狀態。

關鍵字

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並列摘要


Concurrent chemoradiation for locoreginal anal cancer has been prescribed since 1970's. We presented a 42-year-old male patient with locally advanced squamous cell carcinoma of anal canal. The radiation therapy was given at a dosage of 5,040 cGy to the primary tumor and the whole pelvis plus bilateral inguinal area. 5-fluorouracil was given by continuous infusion at a dosage of 1,000 mg/m^2 on days 1-4 of the radiation and repeated on days 29-32. Mitomycin-C was given as a bolus intravenous injection at a dosage of l0mg/m^2 on day 1. Complete remission was achieved 6 weeks after the chemoradiation finished, and the patient was still survived without recurrence at 36 months follow-up.

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