前哨淋巴檢查在早期乳癌的應用

Sentinel Node Biopsy in Early Breast Cancer

俞志誠(Jyh-Cherng Yu) ； 劉自嘉(Tse-Jia Liu)

《中華民國癌症醫學會雜誌》 24卷2期 (2008/04) Pp. 108-111

https://doi.org/10.6588/JCOS.2008.24.2.5

摘要

前哨淋巴切片能非常精確評估乳癌患者的腋下淋巴有否轉移，而前哨淋巴切片對於較小或觸摸不到的乳癌尤其適合。如果前哨淋巴沒被癌細胞轉移，則可免除腋下淋巴手術。然而前哨淋巴切片能否成功，與乳房外科醫師與病理科醫師的經驗有絕對的關係。至目前為止，使用前哨淋巴切片的方法、染劑或放射線同位素的使用等，尚未標準化，對於使用的時機與方式、注射的部位與注射量、及注射後到前哨淋巴切片的時間皆有爭議，而最近的文獻報告皆指出同時使用染劑與放射線同位素有較高的前哨淋巴發現率。

關鍵字

早期乳癌 ； 前哨淋巴腺 ； 淋巴腺切片檢查 ； 偽陰性

並列摘要

Sentinel node biopsy is a sensitive and reliable sampling technique for determining the axillary status of patients with invasive breast carcinoma. The procedure is particularly suitable for patients with either small palpable or non-palpable tumors who may not need routine axillary lymph node dissection. When SN is found to be negative, unnecessary axillary exploration is avoided, thereby minimizing morbidity. However, success of the procedure is dependent upon the experience of both the surgeon and pathologist. The labeling methods, dyes, and radioisotopes used for the procedure, however, are still not standardized up to date. There is no complete agreement with respect to the type, volume, site of injection, and interval between injection of the labeling agent and surgery. The combined use of radioisotope plus blue dye has been shown to have a higher rate of SN detection by either method alone.

並列關鍵字

early breast cancer ； sentinel lymph node ； lymph node biopsy ； false negative