- 期刊
Dimethyl Pyrazine Ethylamine Hydrochloride Acts as a Calcium Agonist
並列摘要
Dimethyl pyrazine ethylamine hydrochloride (DPEH) is a synthetic analogue that acts through the blockade of calcium channels. The effect of DPEH on vascular smooth muscles was examined in this study using the rat aorta, tail artery and portal vein in vitro. On the portal vein, DPEH had a direct contractile effect that was dependent on the presence of extracellular Ca2+. It produced a depolarization-dependent potentiation of both aortic and portal vein contraction and dose-dependently increased the influx of extracellular calcium ions into aortic smooth muscles. It is therefore concluded that DPEH induces vascular smooth muscle contractility by acting as a calcium agonist.
被引用紀錄
Karuppaiya, P. (2013). In vitro production of anti-cancer compounds, expression of lignan biosynthetic pathway gene(s) and anti-cancer activity of biogenic metal nanoparticles synthesized from Dysosma pleiantha [doctoral dissertation, Chaoyang University of Technology]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0078-2712201314042590
延伸閱讀
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