- 期刊
Synthesis and Biological Activity of 2,6- and 2,7-Disubstituted Anthraquinones
並列摘要
A series of 2, 6- and 2, 7-disubstituted anthraquinones was synthesized and evaluated for inhibition of mast cell and neutrophil degranulation as well as neutrophil superoxide formation. Among them, anthraquinone-2, 7-diearboxylie acid (10c) was the most promising agent. Compound 10c significantly inhibited the PCA reaction and histamine- and LTD4-induced skin reactions in rats.
延伸閱讀
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