花蓮縣五個鄉鎮市國小學童之B型肝炎感染情況

The Status of Hepatitis B Virus Infection of Children in Primary Schools of 5 Countries in Hua - Lien

黃呂津(Lu-Chin Huang) ； 林憲宏(Hsien-Hong Lin) ； 謝銘鈞(Ming-Jium Shieh) ； 林等義(Deeng-Yih Lin) ； 黃熾楷(Chee-Kai Wang)

《慈濟醫學雜誌》 4卷1期 (1992/03) Pp. 19-24

https://doi.org/10.6440/TZUCMJ.199203.0019

摘要

Taiwan is an endemic area of hepatitis B virus (HBV) infection. More than 90% of the adults had been infected and 15-20% were carriers. Hua-Lien County lies on the eastern parts of Taiwan and is relatively isolated from other parts of the island by the Central Mountains. The population of Hua-Lien composed of different groups, including Taiwanese, Hakka, Aborigines, and Mainlanders. There is no current report about the status of HBV infection in HuaLien. A survey of the status of HBV infection in primary schools children of 5 countries in Hua-Lien was conducted by enzyme immunoassay of serum hepatitis B surface antigen (HBsAg) and antibody to HBsAg (anti-HBs) in 1988. A total of 7493 students from 42 primary schools received the examination. The infection rate (positive HBsAg or anti-HBs) was 40.1% and the carrier rate (positive HBsAg) was 15.0%. The infection rate of 4053 boys was 41.1% and the carrier rate was 17.0%. The infection rate of 3386 girls was 39.0% and the carrier rate was 12.6%. The carrier rate of boys was higher than the carrier rate of girls (p＜0.001). The infection rate of different primary schools varied from 12.5% to 77.8% and the carrier rate varied from 0% to 50.0%. No significant trends were found with age. We concluded that the overall HBsAg carrier rate and HBV infection rate of 7493 students were similar to those of the general population. The HBsAg carrier rate of boys was higher than that of girls, a point to be investigated further. The infection rate and carrier rate varied from school to school and probably was due to regional variability of the composition of population.

關鍵字

B型肝炎病毒感染 ； B型肝炎病毒表面抗原帶原者

並列摘要

Taiwan is an endemic area of hepatitis B virus (HBV) infection. More than 90% of the adults had been infected and 15-20% were carriers. Hua-Lien County lies on the eastern parts of Taiwan and is relatively isolated from other parts of the island by the Central Mountains. The population of Hua-Lien composed of different groups, including Taiwanese, Hakka, Aborigines, and Mainlanders. There is no current report about the status of HBV infection in HuaLien. A survey of the status of HBV infection in primary schools children of 5 countries in Hua-Lien was conducted by enzyme immunoassay of serum hepatitis B surface antigen (HBsAg) and antibody to HBsAg (anti-HBs) in 1988. A total of 7493 students from 42 primary schools received the examination. The infection rate (positive HBsAg or anti-HBs) was 40.1% and the carrier rate (positive HBsAg) was 15.0%. The infection rate of 4053 boys was 41.1% and the carrier rate was 17.0%. The infection rate of 3386 girls was 39.0% and the carrier rate was 12.6%. The carrier rate of boys was higher than the carrier rate of girls (p＜0.001). The infection rate of different primary schools varied from 12.5% to 77.8% and the carrier rate varied from 0% to 50.0%. No significant trends were found with age. We concluded that the overall HBsAg carrier rate and HBV infection rate of 7493 students were similar to those of the general population. The HBsAg carrier rate of boys was higher than that of girls, a point to be investigated further. The infection rate and carrier rate varied from school to school and probably was due to regional variability of the composition of population.

並列關鍵字

hepatitis B virus infection ； HBsAg carrier