本研究的目的在瞭東部地區冠狀動脈疾病與各危險因子間之相關性,以病歷回溯法收集自1993年5月至1995年6月在慈濟醫院因評估心臟功能而接受心導管檢查且行冠狀動脈血管攝影者共328人。其中本省籍281人,原住民47人。在197位(60.1%)有冠狀動脈疾病者中,其平均年齡、高血壓比率及抽煙量均較冠狀動脈正常者為高,且血中膽固醇平均為196.9±4.02mg/dl較正常者183.3±5.03mg/dl為高,另外高密度脂蛋白(HDL-C)平均為39.8±0.81mg/dl較正常者42.9±1.16mg/dl為低,至於三酸甘油脂則無顯著的差異。而種族與冠狀動脈疾病由於原住民罹患冠狀動脈疾病之比率較低(36.17%),但各危險因子與種族間則無顯著之相關,因此,種族的差異可能在冠狀動脈疾病中扮演了一個重要的角色。
The purpose of this study is to investigate the risk factors of coronary artery disease (CAD) in population of eastern Taiwan. The clinical data of 328 patients(including 47 aborigines), who underwent cardiac catheterization and coronary for cardiac evaluation from May 1993 at Tzu Chi general hospital, were reviewed. There were 197(60.1%) patients with coronary artery disease. The mean age, incidence of hypertention, and amount of smoking were higher in patients with CAD than the ones without CAD. The plasma levels of T-cholesterol, HDL-C(high density lipoprotein cholesterol) were distinctly different between patients with CAD and the ones without CAD(196±4.0mg/dl vs 183±5.0mg/dl,p<0.05; 39.8±0.8mg/dl vs 42.9±1.2mg/dl; P<0.05). There were no significant difference in TG(Triglyceride) between the two groups. In terms of racial difference, aborigines had lower incidence of CAD than non-aborigines(180/281 vs 17/47, P<0.0001). Since there were no significant difference in other risk factors between these two groups, racial difference might be a factor influencing the incidence of CAD. However, the nature of its impact requires further study.