由於台灣的近視行率很高,為了探討家庭遺傳及環境因素對於高度近視發生及進行的影響,我們收集台灣大學新生患有近視,並有有效近視病史、家庭的翗光狀態以及使用視殙的習慣記錄的大學學生,並將所得的數據進行分析比較。 結果顯示居住在台灣的高度近視患者,發生近視的年紀非常年輕(10歲)。比較高度及低度近視患者的使用視力習慣上,並沒有統計上的差別。然而在高度近視學生樣本中,其父母及兄弟姐妹患有近視以及其較早發生近視的比率,有較高及有意義的差別。高度近視經常與發生過早及有族相關性可能源於基因遺傳,但近視發生是否因於顯性基因或環境因素或是兩者,仍然不明瞭。(慈濟醫學1998;10:19-27)
This study was conducted to evaluate the role of familial and environmental factors in the development and progression of high myopia. Myopic college students who had valid record of past history of myopia, family refractive history and visual habits were selected for comparison. The age-onset of low and high myopia in Taiwan was much younger than in Europe or The United States. No significant difference was found in visual habits between subjects with high and los myopia. High myopic subjects had a significantly higher ratio dof myopic parents and siblings, and earlier onset. High myopia is usually early-onset, may be family-related and is perhaps genetic in origin. However, it remains unclear wheter myopia is predominantly due to genetic or environmental factors, or both.(Tzu Chi Med J1998;10:19-27)