運動療法對急性心肌梗塞患者運動耐受力、血液動力以及膽固醇變化之影響－不同年齡層之探討－

The Exercise Capacity, Hemodynamic Responses and Serum Total Cholesterol Change of Patients with Acute Myocardial Infarction in Exercise Therapy: The Influence of Age

李志偉(Chih-Wei Lee) ； 陳復銓(Fu-Chean Chen) ； 王志鴻(Ji-Hung Wang) ； 林俊龍(Chin-Lon Lin) ； 謝仁哲(Jen-Jer Hsieh) ； 張芙美(Fwu-Mei Chang)

《慈濟醫學雜誌》 11卷2期 (1999/06) Pp. 139-146

https://doi.org/10.6440/TZUCMJ.199906.0139

摘要

Objective: To analyze the influence of age on the exercise capacity, hemodynamic responses and serum lipid change of patients with acute myocardial infarction (AMI) in exercise therapy. Patients and Methods: We compared the exercise capacity, hemodynamic responses, and serum lipid levels between patients those over 60 years (group A, n=38) of age and those under 60 (group B, n=31). Male patients with one vessel disease and AMI were selected as subjects. The exercise intensity was prescribed individually using each patient’s target heart rate, which was determined at the anaerobic threshold (AT) point of the exercise testing before exercise training. Extercise training (phase II) began on the 20th day after AMI and continued for 8 weeks at a frequency of three times per week. Ramp-pro-grammed cycle-ergometer tests were performed before and after the exercise training program. The AT, maximal symptom-limited exercise capacity, heart rate (HR), systolic blood pressure (SBP), body mass index (BMI), total cholesterol (TC) level, high density lipoprotein cholesterol (HDL-C) level, and low density lipoprotein cholesterol (LDL-C) level were evaluated for each patient before and after exercise training. Results: Exercise training increased the exercise capacity in both group A and group B significantly. In group B, the resting SBP decreased significantly and the HR and SBP at the AT point after exercise training did not change significantly. LDL-C level decreased significantly in both group A and group B but TC level decreased significantly in group A only. Conclusion: This study indicated that exercise therapy improved the exercise capacity in all patients but its effects on both hemodynamic responses and the serum lipid levels were not the same between groups A and B.

關鍵字

運動療法 ； 年齡 ； 運動耐受力 ； 血液動力變化 ； 血清脂質

並列摘要

Objective: To analyze the influence of age on the exercise capacity, hemodynamic responses and serum lipid change of patients with acute myocardial infarction (AMI) in exercise therapy. Patients and Methods: We compared the exercise capacity, hemodynamic responses, and serum lipid levels between patients those over 60 years (group A, n=38) of age and those under 60 (group B, n=31). Male patients with one vessel disease and AMI were selected as subjects. The exercise intensity was prescribed individually using each patient’s target heart rate, which was determined at the anaerobic threshold (AT) point of the exercise testing before exercise training. Extercise training (phase II) began on the 20th day after AMI and continued for 8 weeks at a frequency of three times per week. Ramp-pro-grammed cycle-ergometer tests were performed before and after the exercise training program. The AT, maximal symptom-limited exercise capacity, heart rate (HR), systolic blood pressure (SBP), body mass index (BMI), total cholesterol (TC) level, high density lipoprotein cholesterol (HDL-C) level, and low density lipoprotein cholesterol (LDL-C) level were evaluated for each patient before and after exercise training. Results: Exercise training increased the exercise capacity in both group A and group B significantly. In group B, the resting SBP decreased significantly and the HR and SBP at the AT point after exercise training did not change significantly. LDL-C level decreased significantly in both group A and group B but TC level decreased significantly in group A only. Conclusion: This study indicated that exercise therapy improved the exercise capacity in all patients but its effects on both hemodynamic responses and the serum lipid levels were not the same between groups A and B.

並列關鍵字

exercise training ； age ； exercise capacity ； hemodynamic responses ； serum lipid levels