Sporotrichosis on Face Successfully Treated with Itraconazole-A Case Report

以Itraconazole成功治療臉部胞子絲菌病－病例報告

洪崧壬(Song-Jen Hong) ； 張中興(Chung-Hsing Chang)

《慈濟醫學雜誌》 18卷3期 (2006/06) Pp. 225-228

https://doi.org/10.6440/TZUCMJ.200606.0225

摘要

胞子絲菌病(Sporotrichosis)主要是由Sporotrix Schenchii所引起的深部黴菌皮膚疾病。最常感染途徑是由皮膚上的傷口。根據每個人不同的免疫反應，除了局部皮膚的侵犯，也會經由淋巴傳遞至全身系統的侵犯。關於我們所發表的病例，是一個發生在正常年輕男性的臉上固定型胞子絲菌病，在皮膚病理切片可以發現有肉芽組織發炎反應和含有胞子多核性巨大細胞，經由黴菌培養所確定診斷。在治療方面，我們是使用itraconazole每天200mg共20週，皮膚上病灶獲得完全的改善，經過6個月的追蹤，也沒有復發的跡象。

關鍵字

胞子絲菌病 ； 臉 ； itraconazole ； 深部黴菌感染 ； Asteroid body

並列摘要

Sporotrichosis is a chronic deep fungal infection caused by Sporotrix schenckii. The most frequent route of infection is via a skin wound. Depending on the immune status, the cutaneous manifestations vary from a fixed lesion on the primary inoculation site to disseminated lesions through lymphogenic spread. Here we report a healthy 40 year-old man with fixed type sporotrichosis on the face. A skin biopsy showed granulomatous inflammation with spores in multinucleated giant cells. Fungal culture and identification revealed the pathogen was Sporotrix schenckii. He was treated with oral itraconazole 200mg daily for 20 weeks with complete resolution of the skin lesion. After 6-months follow up, there was no recurrence.

並列關鍵字

Sporotrichosis ； face ； itraconazole ； deep fungal infection ； Asteroid body