Relationship among Potassium Stimulation Test and Cystoscopic and Cystometric Findings and Bladder Capacity in Patients with Symptoms of Interstitial Cystitis

間質性膀胱炎患者的鉀刺激試驗和膀胱鏡檢、膀胱功能及膀胱容量之相關性

李明輝(Ming-Huei Lee) ； 黃名揚(Ming-Yang Huang)

《臺灣泌尿科醫學會雜誌》 15卷1期 (2004/03) Pp. 9-13

摘要

研究目的：探討間質性膀胱炎患者的鉀離子刺激試驗和膀胱功能、膀胱鏡檢及麻醉下膀胱最大容量之相關性。
材料與方法：從1997年1月至2003年3月共有153位間質性膀胱炎患者接受鉀離子刺激試驗，膀胱功能檢查及膀胱鏡檢。膀胱容積壓力檢查用來測量最大膀胱容量，膀胱鏡檢是在全身麻醉下施行，評估擴張後黏膜下出血的嚴重度及麻醉下最大膀胱容量。使用Student’s t-test來評估其中的相關性。
結果：在153位間質性膀胱炎患者中：127位（83%）為女性，26位（17%）為男性。鉀離子刺激試驗陽性者為110位（72%），陰性者為43位（28%）。膀胱功能最大容積在鉀離子刺激陽性及陰性患者分別為270毫升及299毫升，麻醉下最大膀胱容積在鉀離子刺激陽性、陰性患者分別為672毫升及681毫升。在110位鉀離子刺激試驗陽性病患中，7位（6.4%）膀胱鏡檢為正常，103位（93.6%）呈現擴張後黏膜下出血。然而在43位鉀離子刺激試驗陰性的病患中，4位（9.3%）膀胱鏡檢為正常，39位（90.7%）有擴張後黏膜下出血現象。
結論：鉀離子刺激試驗和膀胱功能最大容積及麻醉下膀胱最大容積並無相關性，鉀離子刺激試驗無法預測膀胱鏡檢的變化。

關鍵字

間質性膀胱炎 ； 鉀離子刺激試驗 ； 黏膜下出血 ； 膀胱容積壓力檢法

並列摘要

OBJECTIVE: To determine relationships among the potassium stimulation test, and the cystoscopic and cystometric findings, and bladder capacity in patients with symptoms of interstitial cystitis.
MATERIALS AND METHODS: From January 1997 to March 2003, 153 patients with symptoms of interstitial cystitis who underwent diagnostic procedures of the potassium stimulation test, cystometry, and cystoscopy were evaluated. Cystoscopy was performed under general anesthesia to evaluate the severity of post-dilatational hemorrhage and maximal bladder capacity. Student’s t-test was used for statistical analysis.
RESULTS: Of the 153 patients who presented with symptoms of interstitial cystitis, 127 (83%) were female and 26 (17%) were male. The potassium stimulation test was positive in 110 (72%) and negative in 43 (28%). Anesthetized maximal bladder capacities averaged 672 and 681 ml in positive and negative potassium tests, respectively. Functional bladder capacities were 270 and 299 ml for the positive and negative potassium tests, respectively. Among the 110 patients with a positive potassium stimulation test, 7 (6.4%) had normal cystoscopic findings, while 103 (93.6%) had moderate or severe post-dilatational hemorrhage. However, among the 43 patients with a negative potassium stimulation test, 4 (9.3%) had normal cystoscopic findings, and 39 (90.7%) had post-dilatational hemorrhage.
CONCLUSIONS: The potassium stimulation test was not correlated with either cystoscopic findings, functional bladder capacity, or anesthetized bladder capacity. The potassium stimulation test could not predict the outcome of cystoscopic findings. These results imply that the potassium chloride test as an aid to a diagnosis of interstitial cystitis should be further evaluated.

並列關鍵字

interstitial cystitis ； potassium test ； glomerulation ； cystometry