Castleman’s disease, or angiofollicular lymph node hyperplasia, is a rare atypical lymphoproliferative disorder. Few cases have been reported in relation to the upper urinary tract or a pararenal location, and only 1 case has been reported in the kidney in the world literature. We report on a 50-year old male with solitary Castleman’s disease of hyaline-vascular type located in the middle pole of the left kidney. The patient underwent frozen sectioning of the lesion followed by a radical nephrectomy. There was no evidence of disease recurrence in 2 years of follow-up after surgery. The relevant literature is reviewed.