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Treatment of Symptomatic Large Simple Cysts of the Kidney-A Comparison of Povidone-Iodine Sclerotherapy with Laparoscopic Unroofing

有症狀大型腎臟單純囊腫的治療-比較經皮抽吸加Povidone-iodine單次硬化治療及腹腔鏡囊腫除頂術的效果

摘要


研究目的:比較對有症狀大型腎臟單純囊腫的兩種治療方法:超音波引導下抽吸加上povidone-iodine硬化治療及腹腔鏡囊腫除頂術的治療效果。 材料與方法:分析本院共20位罹患有症狀單純性腎臟囊腫(最大直徑均大於8公分)病患,其中10位接受超音波引導下抽吸加上單次povidone-iodine硬化治療,另外10位接受後腹腔鏡囊腫除頂術治療,分析其治療及追蹤的結果,並比較兩組的差異。平均追蹤時間為11.3週。結果:10例(100%)後腹腔鏡囊腫去蓋術均無明顯再發(囊腫直徑小於4公分),10位(100%)病患皆有成功的效果(症狀緩解,囊腫最大徑減少超過50%),有8位囊腫消失不見,術後住院平均3.3天。而在10位接受超音波引導下抽吸加上povidone-iodine硬化治療,僅有1例(10%)無明顯再發,僅2例(20%)達成功之治療,並無人囊腫消失不見。兩組病人均無手術併發症。 結論:腹腔鏡腎囊腫除頂術,對於大型的單純腎臟囊腫(直徑大於8公分)治療效果明顯比超音波引導下抽吸加上單次 povidone-iodine硬化治療好,可考慮作為第一線的治療。

並列摘要


OBJECTIVE: To evaluate the efficacy of treatment of symptomatic large simple cysts of the kidney, we retrospectively analyzed the results of laparoscopic unroofing and compared them with the results of echo-guided percutaneous aspiration with povidone-iodine sclerotherapy. MATERIALS AND METHODS: Of a total of 20 patients with a symptomatic large simple cyst of the kidney (with a maximal diameter of > 8 cm in all cysts), 10 patients underwent laparoscopic unroofing and another 10 patients underwent single-session povidone-iodine solution instillation after echo-guided aspiration of the cystic fluid. We compared the resolutions of renal cysts and symptoms in a mean of follow-up 11.3 weeks. Successful treatment was defined as relief of symptoms and a decrease in the cyst maximal diameter of over 50%. RESULTS: The success rate in the laparoscopic unroofing group was much better than in the sclerotherapy group. All patients undergoing laparoscopic unroofing obtained a successful result (100%), while and only 20% of patients in the scierotherapy group achieved successful results (p<0.001). No major complications were noted in either group. CONCLUSIONS: For a symptomatic large renal cyst with a maximal diameter exceeding 8cm, laparoscopic unroofing achieved excellent results which were better than those with povidone-iodine sclerotherapy. Laparocopic unroofing can be considered as the first-line therapy in such patients.

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