Amebic infection, which presented as acute diarrheal symptom or asymptomatic chronic carrier status in the intestinal infection, is caused by the protozoa Entamoeba histolytica. It can also induce extra-intestinal infection. Liver abscess is the most common among them. We report a case of amebic colitis complicated with liver abscess, presenting with bloody diarrhea, abdominal pain and fever. Initial diagnosis was from patient's history, clinical symptoms, and colonoscopic findings, whereas we finally diagnosed on positive Indirect hemagglutination test >1:512. The risk factor in this patient is HIV infection. Ultrasound of abdomen was conducted because of abnormal liver function tests and it revealed liver abscess. In an amebic colitis victim with impaired liver function, abdominal ultrasound is helpful in making an early diagnosis. After prompt antiamebic treatment with metronidazole, patient's bowel symptoms subsided, and the liver lesions resolved without drainage.