Pulmonary Thromboembolism Superimposed on Obstructive Sleep Apnea: A Case Report

阻塞性睡眠呼吸終止症候群患者併發肺栓塞：一病例報告

柯仰謦(Yang-Ching Ko) ； 李冠華(Kuan-Hua Lee) ； 趙亞孟(Ya-Meng Chao) ； 黃德兒(Der-Ear Huang)

《內科學誌》 18卷6期 (2007/12) Pp. 350-355

https://doi.org/10.6314/JIMT.2007.18(6).06

摘要

非侵入性陽壓呼吸輔助器是阻塞性睡眠呼吸終止症候群常用的有效治療方式。但是，一位阻塞性睡眠呼吸終止症候群患者在持續穩定使用陽壓呼吸輔助器五年後，出現活動喘息的症狀並診斷為肺栓塞。阻塞性睡眠呼吸終止症候群確實會導致心血管疾病併發症的風險增加，令人擔憂的是在標凖治療方法，陽壓呼吸輔助器的使用之下，卻無法排除肺栓塞這種致命的併發症。顯然阻塞性睡眠呼吸終止症候群和肺栓塞之間的病生理學關聯性還有待確認；無論如何，阻塞性睡眠呼吸終止症候群患者再使用陽壓呼吸輔助器後，仍需嚴密注意這種致命併發症發生的可能性。

並列摘要

Non-invasive ventilation with continuous positive airway pressure is gaining popularity as a technique for achieving effective treatment in obstructive sleep apnea. However, we observed a patient at our institution complaining of dyspnea on exertion who was diagnosed with pulmonary embolism even after implementation of continuous positive airway pressure for 5 years. This is a worrying problem because obstructive sleep apnea is known to be a risk for cardiovascular complications, and treatment by the mainstay therapy with continuous positive airway pressure didn't seem to eliminate the fatal complication of pulmonary embolism. The association of pathophysiology between obstructive sleep apnea and pulmonary embolism is uncertain; nevertheless, close monitoring is vital to exclude a pathological and fatal event such as pulmonary embolism even after implementation of continuous positive airway pressure.

並列關鍵字

Pulmonary thromboembolism ； Obstructive sleep apnea ； Continuous positive airway pressure