Congestive heart failure is a major burden in modern society. Cardiac resynchronization therapy (CRT) improves cardiac function by allowing the ventricle to contract in a synchronized mode. By breaking the vicious cycle of heart failure, CRT reverses cardiac remodeling and therefore increases heart contractility. Not only does CRT improve the symptoms of heart failure, but it also prolongs the survival of heart failure patients, as shown in clinical trials. All physicians, including primary care physicians, should know this new therapeutic option and be familiar with the related issues.