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食道鱗狀上皮癌現今治療進展

Basic and Clinical Reviews of Esophageal Squamous Cell Carcinoma

摘要


食道癌位居國人2016年十大癌症死因第九位,且男性死亡率遠遠高於女性,彼此相差十五倍有餘。而食道鱗狀上皮癌占了所有食道癌的八成,是一種高度侵襲性的癌症,只有不到四分之一的病人能活超過五年;更因為嚴重的腫瘤相關併發症如無法進食、廔管等,令人聞之色變。不過近年來隨著內視鏡技術的進步、化療和放射治療的發展,能夠更早的發現及更好的治療食道癌,大大改善了病人的預後。本文回顧了最近幾年食道鱗狀上皮癌的最新發展和臨床研究報告,從盛行率、致病因子、基因、診斷和治療方法等方面來剖析食道鱗狀上皮癌,期待對於臨床工作者有所幫助。

並列摘要


In 2016, esophageal cancer was the ninth most common cause of cancer death in Taiwan. Moreover, the mortality rate in men was 15 times higher than that in women. Squamous cell carcinoma accounts for 80% of esophageal cancer. It is a highly invasive cancer, and symptoms include dysphagia, fistulas, and bleeding. Less than 25% of patients survive for 5 years or more. Recent progress in endoscopic techniques has led to earlier detection of esophageal cancer, and with developments in chemoradiotherapy the prognosis has improved greatly. The present article reviews the latest developments and clinical research in esophageal squamous cell carcinoma, including the prevalence, pathogenic mechanisms, and genetic factors. Diagnostic modalities and current treatment options are discussed to help clinicians.

並列關鍵字

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被引用紀錄


鍾雅亘、鄭惠蘭(2021)。照顧一位食道癌病人面對死亡焦慮之護理經驗腫瘤護理雜誌21(),95-106。https://doi.org/10.6880/TJON.202112/SP_21.08
曾鈺評、吳儀君、黃弘暄(2024)。一位食道癌個案首次行氣管及空腸造口術之護理經驗高雄護理雜誌41(2),130-140。https://doi.org/10.6692/KJN.202408_41(2).0012
楊秀霞、姚美惠、吳素綿、何秀玉(2021)。一位初次診斷食道癌第四期患者之護理經驗彰化護理28(3),115-127。https://doi.org/10.6647/CN.202109_28(3).0013
李佩珊、李美樺(2022)。照護一位食道癌術後患者之護理經驗長庚護理33(2),96-105。https://doi.org/10.6386/CGN.202206_33(2).0009
王麗晴、廖敏季(2021)。一位老年食道癌病人行空腸造口之護理經驗領導護理22(2),96-111。https://doi.org/10.29494/LN.202106_22(2).0007

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