急性肝衰竭是一種罕見但嚴重的臨床症候群,其症候預後多為不佳,且高死亡率的疾病。其主要特徵為沒有肝臟疾病的人,其肝機能突然喪失,並造成身體許多器官與系統的影響。造成急性肝衰竭可歸因於藥物使用不當、病毒感染或其他原因。急性肝衰竭患者在快速診斷與適當的醫護處置,重症加護醫療和肝移植已可降低死亡率。平時應審慎使用藥物、慢性肝炎患者應定期追踪檢查,可避免急性肝衰竭的發生。
Acute liver failure (ALF) is a rare and high mortality disease that condition characterized by the abrupt onset of severe liver injury and affecting many organ systems. The causes of ALF vary-it can be attributed to drugs, viruses, and other uncommon sources. Successful care of the ALF patient begins with early diagnosis and triage to the appropriate level of care where a multitude of specialties are required to work together to maximize the chance of recovery. With advances in critical care medicine and emergent liver transplant, ALF mortality rates have gradually decreased.