妊娠期甲狀腺功能亢進的處理：孕婦和胎兒兩面兼俱

The Management of Hyperthyroidism During Pregnancy: From Maternal and Fetal Aspects

陳瑜忻(Yu-Hsin Chen) ； 龔信宗(Shinn-Tzong Gong) ； 林慶齡(Ching-Ling Lin) ； 黃莉棋(Li-Chi Huang)

《內科學誌》 29卷5期 (2018/10) Pp. 305-308

https://doi.org/10.6314/JIMT.201810_29(5).04

摘要

目前已知孕婦甲狀腺功能亢進對胎兒具有嚴重的不利影響。因此，如果可能，對甲狀腺功能亢進(hyperthyroidism)的孕婦應盡早治療，降低母體甲狀腺功能亢進對其本身以及對胎兒的不良影響。對於治療藥物的選擇、開刀的適應症與時機，及^(131)I的輻射危害之了解是不可或缺的。本文包含孕婦甲狀腺功能亢進，其檢驗判讀與診斷，對胎兒所造成的危害，以及相關的治療。

關鍵字

妊娠(Pregnancy) ； 甲狀腺功能亢進(Hyperthyroidism) ； 格雷夫斯病(Graves' disease) ； 甲狀腺刺激素受體抗體(TSH-receptor antibody)

並列摘要

It is well established that maternal hyperthyroidism has adverse effect on fetal development. Therefore it is important to treat maternal hyperthyroidism as early as possible in order to lower the risk of both mother and fetus. It is also necessary to understand the importance of the choice of antithyroid drug, timing and indication of operation, and the radiation danger of 131I. The aim of this article is to discuss the diagnosis and treatment of hyperthyroidism of the pregnant women and its adverse effect to the fetus.