生藥“何首烏”中2,3,5,4'-tetrahydroxystilbene-2-O-glucoside、emodin及physcion的含量分析

Quantitative Analysis of 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside, Emodin, and Physcion in Polygoni Multiflori Radix

陳建志(Chien-Chih Chen) ； 石宜仁(Yi-Zen Shih) ； 黃鈺玲(Yu-Lin Huang) ； 歐潤芝(Jun-Chih Ou)

《中醫藥雜誌》 8卷2期 (1997/06) Pp. 103-110

https://doi.org/10.6940/JCM.199706_8(2).05

摘要

For the identification of the crud drug Polygoni Multitlori Radix, the Standard of Crude Drugs of Japanese Pharmacopeia uses emodin as the indicative substance. Recently, 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside, a bioactive compound from this herb has attracted general attention. In this paper, we examined three compounds 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside, emodin, and physcion as the indicative substances by means of HPLC analysis. We also determined their quantities in the commercial articles containing this herb. Among thirteen samples of the commercial Polygoni Multiflori Radix, the contents of 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside varied greatly, reanging between 0.002 and 0.194%. Another five samples of Polygoni Multiflori Radix extracted powder, the contents of 2,3,5,4'-Tetrahydroxystilbene-2-0-Glucoside fell between 0.016 and 0.544%. Whereas the contents of emodin and physcion ranged between 0.002 and 0.077% in all samples except in the three crud herb samples (No.11-13) where their contents were below 0.001%.

關鍵字

何首鳥 ； 2,3,5,4'-tetrahydroxystilbene-2-O-glucoside ； emodin ； physcion

並列摘要

For the identification of the crud drug Polygoni Multitlori Radix, the Standard of Crude Drugs of Japanese Pharmacopeia uses emodin as the indicative substance. Recently, 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside, a bioactive compound from this herb has attracted general attention. In this paper, we examined three compounds 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside, emodin, and physcion as the indicative substances by means of HPLC analysis. We also determined their quantities in the commercial articles containing this herb. Among thirteen samples of the commercial Polygoni Multiflori Radix, the contents of 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside varied greatly, reanging between 0.002 and 0.194%. Another five samples of Polygoni Multiflori Radix extracted powder, the contents of 2,3,5,4'-Tetrahydroxystilbene-2-0-Glucoside fell between 0.016 and 0.544%. Whereas the contents of emodin and physcion ranged between 0.002 and 0.077% in all samples except in the three crud herb samples (No.11-13) where their contents were below 0.001%.

並列關鍵字

Polygoni Multiflori Radix ； 2,3,5,4'-Tetrahydroxystilbene-2-O-Glucoside ； emodin ； physcion