懷牛膝成分研究

懷牛膝(Achyranthes bidentata B(下標 LUME))爲莧科植物牛膝之乾燥根，具有鎮痛抗發炎、利尿、抗菌及抗痙孿之作用，並對於腰膝酸痛、強筋骨、補肝腎方面有很好的效果。懷牛膝(Achyranthes bidentata B(下標 LUME))的甲醇抽出物，經分離及結構分析，鑑定得到14個化合物，分別是：stigmastero1 和β-sitosterol的混合物、paeono1，palmitic acid，physcion，chrysophanol，stigmasterol-3-O-b-D-g1ucoside 和β-sitosterol-3-O-β-D-glucoside之混合物、oleanolic acid， 5-(hydroxymethyl)-furfura1，1-pa1mityl glycerol，N-trans-feruloy1 3-methyldopamine，oleanolic acid 3-O-β-D-g1ucuronopyranoside 6' methyl ester，ecdysterone，其中paeonol，chrysophanol, (5-hydroxymethy1)-furfura1，1-palmityl glycerol，N-trans-feruloyl-3-methyldopamine五個化合物爲Achyranthes屬植物中首次分離到。

關鍵字

懷牛膝，paeonol ； chrysophanol ； 5-hydroxymethyl-furfural ； 1-palmityl glycerol ； N-trans-feruloyl-3-methyldopamine

並列摘要

Achyranthes bidentata B(subscript LUME) is one of the plant of Amaranthaceae family and possesses analgesic, antiinflammatory, diuretic, antibacterical and anti-convulsive activities. It was used to cure knee pain anti strengthen sinews and bones and also as tonic supplements for liver and kidney. The methanolic extract of this herb was partitioned and separated by chromatographic methods. Fourteen components were obtained. By analyzing their physical, chemical and spectral data, these components were identified as a mixture of stigmasterol and β-sitosterol, paeonol, palmitic acid, physcion, chrysophanol, another mixture of stigmasterol-3-O-β-D-glucoside and β-sitosterol-3-O-β-D-glucoside, oleanolic acid, 5-(hydroxymethyl)-furfural, 1-palmityl glycerol, N-trans-feruloyl 3-methyl-dopamine, oleanolic acid-3-O-β-D-glucuronopyranoside 6'-methyl ester as well as ecdysterone. Among these compounds, paeonol, chrysophanol, 5-(hydroxymethyl)-furfural, 1-palmnityl glycerol, N-trans-feruloyl-3-methyldopamine were isolated from Achyranthes genus for the first time.

並列關鍵字

Achyranthes bidentata ； Paeonol ； Chrysophanol ； 5-Hydroxymethyl-furfural ； 1-Palmitylgl glycerol ； N-trans-Feruloyl-3-methyldopamine

國際替代計量

懷牛膝成分研究

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