固本解鬱法論治中風後抑鬱症(poststroke depression)對照研究

Study of Poststroke Depression Treated by Therapy of Constitution Consolidating and Depression Smoothing

劉慶憲(Qing-Xian Lin) ； 宋永建(Yon-Jian Shong)

《中醫藥雜誌》 13卷2期 (2002/06) Pp. 81-88

https://doi.org/10.6940/JCM.200206_13(2).04

摘要

To investigale the relationship between the therapy constitution consolidating and depression smoothing (固本解鬱法) and the improvement of poststroke depression (PSD). 162 patients with PSD in treatment group took tonic to the heart and spleen & smooth depression decoction (心脾解鬱湯), 150 patients with PSD in control group took amitriptyline. The treatment course was 4 weeks. After patients with PSD had been treated for 2,4 weeks, respectively, the total mark and the mark of each of our factors assessed by HAMD in treatment group were significatly lower than thosein control group (P＜0.01), The side effects of treatment group were less than those of control group (P＜0.05). The base pathogenesis of PSD is related to cerebral infarction or hemorrhage after apoplexy. The therapeutic effect of tonic to the heart and spleen & smooth depression decoction (心脾解鬱湯) on PSD is superior to that of traditional anti-depression drugs, without obvious side effects.

關鍵字

固本解鬱 ； 中風後抑鬱症 ； 心脾解鬱湯 ； 阿米替林

並列摘要

To investigale the relationship between the therapy constitution consolidating and depression smoothing (固本解鬱法) and the improvement of poststroke depression (PSD). 162 patients with PSD in treatment group took tonic to the heart and spleen & smooth depression decoction (心脾解鬱湯), 150 patients with PSD in control group took amitriptyline. The treatment course was 4 weeks. After patients with PSD had been treated for 2,4 weeks, respectively, the total mark and the mark of each of our factors assessed by HAMD in treatment group were significatly lower than thosein control group (P＜0.01), The side effects of treatment group were less than those of control group (P＜0.05). The base pathogenesis of PSD is related to cerebral infarction or hemorrhage after apoplexy. The therapeutic effect of tonic to the heart and spleen & smooth depression decoction (心脾解鬱湯) on PSD is superior to that of traditional anti-depression drugs, without obvious side effects.

並列關鍵字

Poststroke depression ； Consolidate the constitution and smoothing depression method ； Tonic to the heart and spleen & smooth depression decoction ； Amitriptyline