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非小細胞肺癌之手術後放射線治療

Postoperative Radiotherapy for Non-Small Cell Lung Cancer

摘要


Forty patients with non-small cell carcinoma of lung had received postoperative radiotherapy between January 1983 and June 1985 at Cancer Therapy Department, Veterans General Hospital Taichung. There were 36 males and 4 females. Their age were 21-76 with median age of 60. All patients had received 4,000 cGy TD/10 fractions/5-6 weeks, to the tumor bed area and mediastiunm with split-course. The overall 2-year surviaval was 47.5% (19/40), median survival time was 16.5 months. The 2 years survival of parients with squamous cell carcinoma and adenocarnoma were 65% and 40%, with median survial time of 26 and 16 months (P>0.05) respectively. Patients with mediastinal nodes metastases has had 2-year survival of 35.3% with median survival time of 15 months VS 55.6% and 26 months for hialr node metastases only (P>0.05). Prophylactic irradiation to the supraclavicular fossa with dose more than 4,000 cGy/10 fraction/5-6 weeks appeared beneficial to prevent from the supraclavicular lymph node metastasis.

並列摘要


Forty patients with non-small cell carcinoma of lung had received postoperative radiotherapy between January 1983 and June 1985 at Cancer Therapy Department, Veterans General Hospital Taichung. There were 36 males and 4 females. Their age were 21-76 with median age of 60. All patients had received 4,000 cGy TD/10 fractions/5-6 weeks, to the tumor bed area and mediastiunm with split-course. The overall 2-year surviaval was 47.5% (19/40), median survival time was 16.5 months. The 2 years survival of parients with squamous cell carcinoma and adenocarnoma were 65% and 40%, with median survial time of 26 and 16 months (P>0.05) respectively. Patients with mediastinal nodes metastases has had 2-year survival of 35.3% with median survival time of 15 months VS 55.6% and 26 months for hialr node metastases only (P>0.05). Prophylactic irradiation to the supraclavicular fossa with dose more than 4,000 cGy/10 fraction/5-6 weeks appeared beneficial to prevent from the supraclavicular lymph node metastasis.

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