A 15-year-old adolescent presented episodic neurologic symptoms including sensory impairment, pyramidal symptoms, cerebellar ataxia and brainstem dysfunction in a relapsing/remitting pattern since 11 years of age. Magnetic resonance imaging (MRI) showed multiple lesion plaques over the right cerebellum, brainstem and bilateral periventricular regions. Definite multiple sclerosis (MS) was clinically diagnosed and high dose of corticosteroid induced dramatic improvement. MS seldom occurs before adolescence, and uncertainty exists concerning its nature and course. MRI is a useful tool in the diagnosis and followup of MS. Child or young adolescent MS more frequently have brainstem and cerebellar lesions, compared with the adult type.