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Magnetic Resonance Imaging of Childhood Multiple Sclerosis: A Case Report

兒童期多發性硬化症之磁振造影:一病例報告

摘要


一位十五歲青少年從十一歲開始,表現出復發性及緩解性的陣發神經症狀,包括感覺異常,錐體症狀,小腦運動失調及腦幹功能異常。磁振造影顯示在右側小腦,腦幹,及兩側腦室周圍有多發性病灶斑塊。診斷為臨床確定型多發性硬化症,經給予高劑量皮質類固醇後症狀明顯緩解。多發性硬化症不常在青春期前發生,且其本質及病程仍未明。磁振造影是診斷及追蹤多嶺性硬化症的利器。與成人型相比,兒童及青春期發作的多發性硬化症較常出現腦幹及小腦病灶。

並列摘要


A 15-year-old adolescent presented episodic neurologic symptoms including sensory impairment, pyramidal symptoms, cerebellar ataxia and brainstem dysfunction in a relapsing/remitting pattern since 11 years of age. Magnetic resonance imaging (MRI) showed multiple lesion plaques over the right cerebellum, brainstem and bilateral periventricular regions. Definite multiple sclerosis (MS) was clinically diagnosed and high dose of corticosteroid induced dramatic improvement. MS seldom occurs before adolescence, and uncertainty exists concerning its nature and course. MRI is a useful tool in the diagnosis and followup of MS. Child or young adolescent MS more frequently have brainstem and cerebellar lesions, compared with the adult type.

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