Nasopharyngeal Carcinoma with Skull Base Invasion and Intracranial Spread: CT Characteristics

鼻咽癌對於顱底及顱內侵犯的電腦斷層表徵

黃駿麟(Chun-Lin Huang) ； 陳啟昌(Clayton Chi-Chang Chen) ； 李三剛(San-Kan Lee)

《中華放射線醫學雜誌》 23卷1期 (1998/02) Pp. 15-19

摘要

鼻咽癌經常造成顱底及顱內的侵犯。我們利用電腦斷層檢查來幫助確定診斷，並探討腫瘤侵犯的途徑。在過去5年，總共103個病理診斷確定為鼻咽癌的病人接受了分析。每一個人均接受了注射對比劑後的軸狀及冠狀切面電腦斷層檢查。分析結果，其中52個病人有腫瘤顱底的侵犯，同時合併顱內侵犯的有40個人。而在51個無顱底侵犯的病人中，有一人發現有顱內海綿竇的侵犯。對於顱底的侵犯，以蝶竇及破裂孔最常被見。顱內則以海綿竇及顱中窩最易被侵犯。其中侵犯海綿竇的途徑，以經過破裂孔往顱內侵犯最常見。事實上，鼻咽癌時常同時造成顱底及顱內多處的侵犯，利用電腦斷層軸狀及冠狀切面檢查，不僅可以幫助確定診斷。更可以讓我們清楚的看到腫瘤侵犯的途徑。

關鍵字

鼻咽，腫瘤 ； 顱，解剖學 ； 顱，底部 ； 顱，電腦斷層

並列摘要

Nasopharyngeal carcinoma (NPC) frequently invades the skull base and spreads intracranially. While we used CT scans to identify NPC with skull base invasion and intracranial spread, the routes of tumor infiltration were also studied. Of the one hundred and three patients retrospectively studied, fifty-two patients had skull base bony erosion, and forty had combined intracranial spread. Fifty-one patients had no evidence of skull base bony destruction, but one of them had cavernous sinus involvement. While sphenoid sinus, foramen lacerum and clivus were the most common sites of skull base invasion, intracranial spread occured most frequently in cavernous sinus, middle cranial fossa and posterior cranial fossa. The most common route of cavernous sinus spread was through the foramen lacerum, followed by sphenoid sinus destruction. CT scan with axial and coronal sections can help us to clearly define the routes of tumor infiltration.

並列關鍵字

Nasopharynx, neoplasm ； Skull, anatomy ； Skull, base ； Skull, CT