Atypical Carcinoid Tumor of the Thymus:A Case Report

非典型胸腺纇癌：一病例報告

溫清珠(Ching-Chu Wen) ； 陳友強(Yu-Chiang Chen) ； 許耀平(Yao-Peng Hsu) ； 許明輝(Ming-Huei Sheu)

《中華放射線醫學雜誌》 28卷5期 (2003/10) Pp. 317-321

摘要

胸腺類癌（即原發性神經內分泌胸腺瘤）為一種罕見腫瘤，其細胞分化良惡之間涵蓋甚廣。茲報導一例前縱膈腔腫瘤，證實為非典型胸類腺癌，並具有「中等程度分化的非典型神經內分泌癌」之組織病理性質。同時也討論該例之其臨床表徵、影像學發現與病理學診斷。本例在影像學上表現大區域壞死，適可印證組織病理分化等級，較為特殊。由於胸腺類癌具有局部侵犯及遠處轉移之傾向，當X光或電腦斷層（CT）片辨識出前縱膈腔腫瘤時，必須將其納入鑑別診斷。並期待大區域壞死之影像特徵能預測此類腫瘤的組織病理分級。

關鍵字

胸腺類腫瘤 ； 神經內分泌腫瘤 ； 縱膈腔 ； 電腦斷層攝影

並列摘要

Carcinoid tumor of the thymus is a rare neoplasm, It comprises a wide spectrum of lesions ranging from well-differentiated to poorly-differen-tiated neoplasms. We report a case of anterior mediastinal mass, which is proven to be an atypical thymic carcinoid tumor with a histopathological nature of intermediate-grade moderately-differentiated neuroendocrine carcinoma. We also present the patient's clinical manifestations, imaging findings and pathological diagnosis. This tumor reveals large area of necrosis in imaging finding, which corresponds with its histopathological differentiation and classification. Since the thymic carcinoid had a tendency of local invasion and distant metastasis, it should be included in the differential diagnosis of anterior mediastinal tumor identified on chest X-ray or CT films. The imaging finding of large necrotic area can be predictable in its histopathological grading.

並列關鍵字

Computed tomography ； Mediastinum ； Neuroendocrine carcinoma ； Thymic carcinoid