Blowing fog method was applied for evaluating cooling effect in open-type greenhouse with natural ventilation. Experiments were conducted to calculate the quantities of nozzles and natural evaporation by VETH chart for local climates in this study. By using the time interval spraying, the temperature reduction test showed the indoor temperature designed can not be reached due to low evaporation rate. Therefore, in this situation it was needed to increase the quantities of nozzles. If the continuous spraying was used, indoor temperatures were lower than outdoor temperature for 1~2℃ before indoor air was saturated. Indoor temperatures of greenhouse with blowing fog were lower than those with natural ventilation for 3~5℃. It showed that the reasonable designing blowing fog system can reduce the indoor temperature with less nozzles, which can be applied to the open-type greenhouse in Taiwan.