環境質譜技術在新興污染物檢測的應用與發展

Application of Environmental Mass Spectrometry in Emerging Contaminants Analysis

丁望賢(Wang-Hsien Ding) ； 陳鑫昌(Hsin-Chang Chen)

《科儀新知》 168期 (2009/02) Pp. 36-51

https://doi.org/10.29662/IT.200902.0004

摘要

近年來在環境檢測方面，液相層析質譜技術與串聯質譜技術的使用已成為主流。本文介紹這幾年液相層析串聯質譜技術結合大氣壓力游離法（如電灑游離法與大氣壓力光游離法）檢測新興污染物的應用與發展。串聯質譜技術應用於環境定量檢測成為近年來的研究重點，其能有效的降低偵測極限，並提升偵測靈敏度，特別以溴化耐燃劑、全氟烷基磺酸與羧酸類化合物、過氯酸根離子、內分泌干擾物質與荷爾蒙、奈米材料為例說明。在本文中同時也探討混成串聯質譜技術（如四極棒－直交式飛行時間混成串聯式質譜技術、四極棒－線性離子阱質譜串聯技術）應用在檢測複雜基質中藥物殘留物的最新發展。

並列摘要

In this overview article, we discussed the progress of liquid chromatography/mass spectrometry (LC/MS) and LC-tandem MS (LC/MS/MS) in environmental analysis. The article covered challenges and achievements that occurred last couple years for emerging contaminants analysis, especially focusing on brominated flame retardants, perfluorinated surfactants, perchlorate, endocrine disrupting compounds (EDCs) and hormones and nanomaterials. LC/MS coupled with atmospheric pressure ionizations (i.e., electrospray ionization and atmospheric pressure photoionization) continued to dominate the new methods developed and the use of tandem MS technique has become commonplace for quantitative environmental analysis. The applications of newly developed hybrid mass spectrometric techniques, such as quadrupole time-of-flight MS and quadrupole linear-ion-trap MS, for pharmaceutical residues analysis in complex matrices were also introduced.