- 期刊
- OpenAccess
奈米半球結構陣列鎳模仁之製備與其在組織工程支架之製作應用
Nanomolding of Nano-Structured Biodegradable Scaffolds
摘要
本研究以陽極氧化鋁膜（AAO）之背阻障層結構做為模仁的3D奈米結構圖形，於AAO阻障層結構上濺鍍一層金薄膜做為電極，接著利用電鑄技術於此電極上鍍上鎳，最後將AAO蝕刻掉，即得到具有3D奈米結構之鎳模仁。本研究進一步以奈米結構之金屬模仁壓印眾（乳酸一甘醇酸共景物）（PLGA）、眾乳酸（PLA）、幾丁聚醣（Chitosan）等生物可降解材料，製作奈米結構組織工程支架。
關鍵字
無資料並列摘要
In this study, we demonstrate a replica mold fabrication method for nano-hemisphere arrays nanomolding by nickel electroforming using the highly ordered nano-hemisphere array of the barrier-layer surface of an anodic aluminum oxide (AAO) membrane as the master mold. The feature size of the nano-hemispheres can be controlled by the use of different etching solutions for anodic oxidation of aluminum. Using the nickel replica mold, nano-structured tissue engineering scaffolds in poly (lactic-co-glycolic acid) (PLGA), polylactide (PLA), and chitosan were fabricated by casting.
並列關鍵字
無資料延伸閱讀
- Chian, H. F. (2013). 奈米定位平面運動平台之結構設計與改良 [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2013.10119
- 巫清景（2015）。製作奈米模板並探討嵌段共聚物於奈米模板下之自組裝現象〔碩士論文，國立清華大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0016-1802201617055206
- Lin, M. N. (2005). 奈米結構的導引自組織成長模式與一維奈米材料的物性研究 [doctoral dissertation, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU.2005.01229
- Lee, P. W. (2009). Multifunctional biodegradable nanoparticles for biomedical applications [doctoral dissertation, National Tsing Hua University]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0016-2705201013401928
- Dong, M., Liu, L., & Zhang, S. (2016). Nanostructural Biomaterials and Applications. Journal of Nanomaterials, 2016(), 355-356-432. https://doi.org/10.1155/2016/5903201