腹膜偽黏液瘤(Pseudomyxoma Peritonei)一病例列報告及文獻回顧

Pseudomyxoma Peritonei-A Case Report and Review of the Literature

張芳維(Fung-Wei Chang) ； 陳達昌(Da-Chung Chen) ； 余慕賢(Mu-Hsien Yu)

《中華民國婦癌醫學雜誌》 2003年1期 (2003/04) Pp. 45-49

https://doi.org/10.7010/JGO.200304.0045

摘要

腹膜偽黏液瘤是一種瀰漫性黏液腫瘤，黏液散佈於腹腔與骨盆腔。此病症大部分源自於闌尾與結腸。我們報告一位六十九歲女性，六年前於地區醫院因卵巢腫瘤接受手術時，發現有黏液性卵巢腺癌第Ⅲc期(mucinous cystadeno-carcinoma of ovary, stage Ⅲc)，故轉至本院接受進一步治療。經過仔細評估，我們先讓患者接受三個療程的全身性化學治療(induction chemotherapy)，再進行腫瘤減積手術(Interval debulking operation)，術後追加三個療程全身性化學治療。此次因腹膜偽黏液瘤而再次接受腫瘤減積手術併術後全身性化學治療；我們藉此病例來探討腹膜偽黏液瘤形成之機轉及再次腫瘤減積手術併術後全身性化學治療的成效。

關鍵字

腹膜偽黏液瘤 ； 黏液性卵巢腺癌

並列摘要

Pseudomyxoma peritonei is characterized by a gradual expansion of mucoid tumor and fluid within abdominopelvic regions. Most case were of appendiceal origin. Few were of ovarian origin and always as a result of carcinomatosis from mucinous cystadenocarcinoma of ovary. We reported a 69-year-old woman has the diagnosis of pseudomyxoma peritonei with histological confirmation. She was a victim of mucinous cystadenocarcinoma of ovary, stage Tile and she had received suboptimal debulking operation, three courses of induction chemotherapy, interval optimal debulking and three courses of consolidation chemotherapy about 6 years ago. This time, she received secondary surgical debulking with postoperative chemotherapy. It seems to be the necessitated treatment, even though controversies persist.