針對不成熟卵巢畸胎瘤生育能力的保存－一篇病例討論及新知

Fertility-Preservation for Immature Teratoma of the Ovary

陳嘉卉(Chia-Hui Chen) ； 顏明賢(Ming-Shyen Yen) ； 趙灌中(Kuan-Chong Chao) ； 王鵬惠(Peng-Hui Wang)

《中華民國婦癌醫學雜誌》 2006年2期 (2006/10) Pp. 21-25

https://doi.org/10.7010/JGO.200610.0021

摘要

這是一篇一位有關患有末期卵巢畸胎瘤的病患欲保留生育能力治療的報導。一位二十七歲女性，今年產下一名健康男嬰。她本身有不成熟卵巢畸胎瘤的病史，且這不成熟畸胎瘤是不確定期別及第三級分化程度。她在十三歲時接受單側卵巢輸卵管切除術及對側卵巢扇形切除術，接著接受六次的多種藥物結合的化學治療。然後在第二次手術後，發現殘餘腫瘤仍然存在，又接受保留生育能力的保守手術後，再追加額外六次的不同配方的化學治療至疾病完全消除為止。她在開始治療後的十四年後，結婚並產下一健康男嬰。基於這成功的案例，積極保留生育能力的外科手術再加上術後的化學治療，對於患有惡性不成熟卵巢畸胎瘤的病人欲保留生育功能是一種選擇，甚至對於末期或未定期別的患者，亦適用。

關鍵字

保留生育能力 ； 不成熟畸胎瘤 ； 卵巢介紹

並列摘要

Fertility preservation for a patient with advanced immature teratoma of the ovary was reported. A 27-year-old woman, who delivered a healthy baby, was reported. She had a history of the ovarian immature teratoma, grade 3, uncertain stage at her 13 years of age. She was initially treated with unilateral salpingo-oophorectomy and a contralateral wedge resection for tumor invasion, followed by 6-course of the PVB (cisplatin+ vinblastine+ bleomycin) regimen, second operation, and an additional 6-course EP (etoposide and cisplatin) with complete remission. She got married and delivered a healthy bay 14 years after the initial treatment. Based on this successful case, an intensive fertility-preserving surgery followed by chemotherapy, even in advanced-stage immature teratoma of the ovary, may be effective in conserving the reproductive function of woman with malignant immature teratomas of the ovary.

並列關鍵字

fertility-preserved surgery ； immature teratoma ； ovary