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  • 期刊

口服抗生素預防白血球減少之感染

Antibiotic Prophylaxis in Neutropenic Afebrile Patients

摘要


感染是化學治療導致白血球減少後最常見之併發症。最近美國感染症學會是不贊成對無發燒的白血球減少者使用抗生素,但最近許多綜合分析認爲fluoroquinolones可以減少感染,因此建議對無發燒之白血球減少者,考應使用fluoroquinolone來預防感染,但長期之細菌抗藥性則尚未清楚。

並列摘要


Infection remains the most common complication of chemotherapy-induced neutropenia. Current Infectious Disease Society of America guidelines do not endorse routine prophylaxis for neutropenic patients. However, in most of recent studies, the rate of infection among fluoroquinolones treated patients was significantly lower than rates among placebo recipients. Therefore, prophylaxis, preferably with a fluoroquinolone, should be considered for use in neutropenic afebrile patients. The long-term effect of this intervention on microbial resistance in the community is not known.

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