早期子宮頸癌的新保守性治療

The Advance of Conservative Treatment of Early Cervical Cancer

李耀泰(Yiu-Tai Li) ； 陳福民(Fu-Min Chen) ； 沈仁達(Jenta Shen) ； 郭宗正(Tsung-Cheng Kuo)

《中華民國婦癌醫學雜誌》 2009年2期 (2009/10) Pp. 18-23

https://doi.org/10.7010/JGO.200910.0018

摘要

對第Ⅰ期A2至第Ⅰ期B1之早期子宮頸癌，根除性子宮切除和骨盆腔淋巴結摘除一直是標準的治療方法。但許多這類早期子宮頸癌的婦女，仍未完成生兒育女，極望能保留生育能力。第Ⅰ期A1的子宮頸癌單獨以子宮頸錐狀切片便可以治癒；第Ⅰ期A2至第Ⅰ期B1的子宮頸癌，如欲保留子宮，可先接受化學治療，再接受子宮頸錐狀切片和骨盆腔淋巴結摘取，已有多位成功懷孕和生產的例子。當然，患者如選擇這些保守性的治療，一定需要長期縝密的追蹤。

關鍵字

顯微侵犯子宮頸癌 ； 早期子宮頸癌 ； 保守性治療 ； 錐狀子宮頸切除 ； 手術前化學治療

並列摘要

The recommended radical hysterectomy with pelvic lymphadenectomy is the standard therapy for young women with stage IA2-IB1 cervical cancer. However, many women diagnosed with cervical cancer have not completed their childbearing. Cervical conization alone is adequate treatment for patients with stage IA1 cervical cancer. Neoadjuvant chemotherapy followed by conization and pelvic lymphadenectomy may be considered an alternative for young women with stage IA2-IB1 cervical cancer who wish to preserve their fertility potential. Successful pregnancies have been reported after these regimens. Patients who choose conservative therapy must maintain close long-term follow-up.

並列關鍵字

microinvasive cervical cancer ； early cervical cancer ； conservative treatment ； cervical conization ； neoadjuvant chemotherapy