Unprovoked pathological laughter has been associated with various lesions arising from the hypothalamus, cerebral hemispheres, and brainstem. We report a 57-year-old man who presented with episodes of involuntary laughter with increasing frequency over the course of more than 4 years. A large left petroclival meningioma was found. His involuntary laughter has completely subsided after surgical removal and in the follow-up of 3 years.