Risk Factors of Carotid Stenosis in First-Ever Ischemic Stroke in Taiwan: A Hospital-based Study

Chien-Hung Chang ； Yeu-Jhy Chang ； Tsong-Hai Lee ； Kai-Cheng Hsu ； Shan-Jin Ryu

《Acta Neurologica Taiwanica》 15卷4期 (2006/12) Pp. 237-243

https://doi.org/10.29819/ANT.200612.0003

並列摘要

Objective: The aim of this study is to identify the risk factors of extracranial carotid atherosclerosis in patients with first-ever ischemic stroke.
Material and methods: A total of 541 consecutive first-ever ischemic stroke patients were enrolled in the present study. We examined clinical and laboratory factors that were potentially relevant to extracranial carotid artery atherosclerosis. The degree of carotid stenosis was diagnosed based on B-mode ultrasonography.
Results: The sample contained 325 men and 216 women. Among these patients, 80% had a ＜ 50% carotid stenosis and 20% had a ≥ 50% carotid stenosis. Multiple logistic regression analysis revealed that age (odds ratio = 2.15, 95% CI = 1.06~1.11, P ＜ 0.001) and smoking (odds ratio = 1.52, 95% CI = 1.17~3.54, P = 0.012) were significantly associated with ≥ 50% carotid stenosis.
Conclusions: In the present study, age and smoking are found to be the independent risk factors for carotid atherosclerosis. The identification of these risk factors may improve our knowledge in the primary prevention of ischemic stroke in Taiwan.

並列關鍵字

Risk factors ； Carotid atherosclerosis ； First-ever stroke